Journal: Frontiers in Endocrinology
Article Title: Are natural estrogens used in contraception at lower risk of venous thromboembolism than synthetic ones? A systematic literature review and meta-analysis
doi: 10.3389/fendo.2024.1428597
Figure Lengend Snippet: GRADE assessment per meta-analytical model.
Article Snippet: Reed, 2021 ( ) , Prospective study , E2-based COC: - n=44,559 Synthetic estrogens: - n=49,754 , mean age: 30.1 mean BMI: 23.3 21% of smokers 2.4% of family history of VTE , E2-based COC: - E2-NOMAC Synthetic estrogens: - EE-LNG , E2-based COC: - 12/48,846 Synthetic estrogens: - 25/62,337 , Merck Sharp and Dohme, a subsidiary of Merck & Co., Inc., Kenilworth, NJ, USA, and Theramex Ireland Limited, Dublin, Ireland , 9/9 stars.
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